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Please use this identifier to cite or link to this item: http://hdl.handle.net/2241/97858

Title: Myelodysplastic syndrome accompanied by basophilia and eosinophilia with t(5;12)(q31;p13)
Authors: Katsura, Yukitaka
Suzukawa, Kazumi
Nanmoku, Toru
Nemoto, Noriko
Machino, Takayuki
Obara, Naoshi
Okoshi, Yasushi
Mukai-Yamamoto, Harumi
Hasegawa, Yuichi
Kojima, Hiroshi
Kawakami, Yasushi
Nagasawa, Toshiro
鈴川, 和己
Issue Date: Oct-2007
Publisher: Elsevier Inc.
Journal Title: Cancer Genetics and Cytogenetics
Volume: 178
Issue: 1
Start Page: 85
End Page: 88
DOI: 10.1016/j.cancergencyto.2007.05.020
PMID: 17889716
Abstract: The t(5;12)(q31not, vert, similar35;p12not, vert, similar13) is rare among cytogenetically categorized myeloid diseases. Here we describe a case of myelodysplastic syndrome (MDS) with basophilia followed by leukocytosis, basophilia, and eosinophilia with t(5;12)(q31;p13). A 44-year-old man was referred to Tsukuba University Hospital in August 2005, due to severe anemia and thrombocytopenia. Peripheral blood examination showed hemoglobin 4.5 g/dL, with mean corpuscular volume 109 fL, platelets 73 × 109/L, and white blood cells 4.9 × 109/L with 23% basophils, 3% eosinophils, and 0% blasts. Bone marrow was slightly hypocellular, with trilineage dysplasia. Cytogenetic examination of the bone marrow cells revealed a normal karyotype, 46,XY. A diagnosis of myelodysplastic syndrome–refractory anemia with excess blasts type 2 (MDS-RAEB2) was made according to the WHO classification.
URI: http://hdl.handle.net/2241/97858
Rights: ©2007 Elsevier Inc.
Text Version: author
Appears in Collections:Cancer genetics and cytogenetics
鈴川 和己 (Suzukawa Kazumi)

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