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つくばリポジトリ (Tulips-R) >
0 コンテンツタイプ別 (Content type) >
01 雑誌発表論文等 (Journal article, etc.) >
The American journal of cardiology >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/2241/114785
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| Title: | Clinical and Procedural Characteristics of Acute Hemodynamic Responders Undergoing Triple-Site Ventricular Pacing for Advanced Heart Failure |
| Authors: | Yamasaki, Hiro
Seo, Yoshihiro
Tada, Hiroshi
Sekiguchi, Yukio
Arimoto, Takanori
Igarashi, Miyako
Kuroki, Kenji
Machino, Takeshi
Yoshida, Kentaro
Murakoshi, Nobuyuki
Ishizu, Tomoko
Aonuma, Kazutaka
瀬尾, 由広
夛田, 浩
関口, 幸夫
吉田, 健太郎
村越, 伸行
石津, 智子
青沼, 和隆 |
| Issue Date: | Nov-2011 |
| Publisher: | Elsevier |
| Journal Title: | The American journal of cardiology |
| Volume: | 108 |
| Issue: | 9 |
| Start Page: | 1297 |
| End Page: | 1304 |
| DOI: | 10.1016/j.amjcard.2011.06.048 |
| PMID: | 21855835 |
| Abstract: | The advantages of triple-site ventricular pacing (Tri-V) compared to conventional biventricular site pacing (Bi-V) have been reported. We sought to identify the predictors of acute hemodynamic Tri-V responders. Acute hemodynamic studies were performed in 32 patients with advanced heart failure during Tri-V implantation. After the right ventricular (RV) and left ventricular (LV) leads were implanted for a conventional Bi-V system, an additional pacing lead was implanted in the RV outflow tract for Tri-V. The LV peak +dP/dt and tau were measured during AAI, Bi-V, and Tri-V pacing. A Tri-V responder was defined as a patient whose percentage of increase in the peak +dP/dt during Tri-V was >10% compared to of that during Bi-V. The baseline clinical variables and RV outflow tract lead location were analyzed to identify the characteristics of the Tri-V responders. Of the 32 patients, 10 (31%) were classified as Tri-V responders. The LV end-diastolic volume was greater (246 ± 48 vs 173 ± 53 ml, p <0.01), and the RV outflow tract lead was implanted at a greater outflow tract portion (p <0.05) in the Tri-V responders. Multivariate analysis revealed that only the baseline LV end-diastolic volume (per 50-ml greater) predicted the Tri-V response (odds ratio 2.87, 95% confidence interval 1.03 to 8.00, p <0.05). The area under the receiver operating characteristic curve for the LV end-diastolic volume was 0.84 (p <0.01) and an LV end-diastolic volume of >212 ml had a sensitivity of 80% and specificity of 77% to distinguish Tri-V responders. In conclusion, Tri-V provides greater hemodynamic effect for patients with a larger LV end-diastolic volume owing to its resynchronization effects on the LV anterior wall. |
| URI: | http://hdl.handle.net/2241/114785 |
| Rights: | © 2011 Elsevier Inc.
“NOTICE: this is the author's version of a work that was accepted for publication in The American journal of cardiology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in PUBLICATION, Vol108(9),2011,DOI:10.1016/j.amjcard.2011.06.048” |
| Text Version: | publisher |
| Appears in Collections: | 瀬尾 由広 (Seo Yoshihiro)
夛田 浩 (Tada Hiroshi)
関口 幸夫 (Sekiguchi Yukio)
吉田 健太郎 (Yoshida Kentaro)
村越 伸行 (Murakoshi Nobuyuki)
石津 智子 (Ishizu Tomoko)
青沼 和隆 (Aonuma Kazutaka)
The American journal of cardiology
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