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Please use this identifier to cite or link to this item: http://hdl.handle.net/2241/103727

Title: Vision-Related Quality of Life and Visual Function Following Vitrectomy for Proliferative Diabetic Retinopathy
Authors: Okamoto, Fumiki
Okamoto, Yoshifumi
Fukuda, Shinichi
Hiraoka, Takahiro
Oshika, Tetsuro
岡本, 史樹
岡本, 芳史
平岡, 孝浩
大鹿, 哲郎
Issue Date: Jun-2008
Publisher: Elsevier Inc.
Journal Title: American journal of ophthalmology
Volume: 145
Issue: 6
Start Page: 1031
End Page: 1036.e1
DOI: 10.1016/j.ajo.2008.02.006
PMID: 18400203
Abstract: Purpose To evaluate the vision-related quality of life (VR-QOL) and visual function following vitrectomy for proliferative diabetic retinopathy (PDR). Design Prospective, interventional, consecutive, comparative case series. Methods The 25-Item National Eye Institute Visual Function Questionnaire (VFQ-25) was answered by 51 patients with PDR before and three months after 20-gauge pars plana vitrectomy. Among the patients with PDR, 30 underwent combined cataract surgery and vitrectomy. Clinical data were collected, including logarithm of minimal angle of resolution (logMAR) best-corrected visual acuity (BCVA), letter contrast sensitivity, and metamorphopsia. The VFQ-25 was also administered to 46 age-matched normal controls. Results The preoperative VFQ-25 composite score was significantly lower in the PDR patients (56.3 ± 18.8, mean ± standard deviation) than in the normal controls (85.2 ± 10.3; P < .0001). Vitrectomy significantly improved VFQ-25 composite score (P < .005) and eight of 12 subscales (P < .05). The preoperative VFQ-25 composite score significantly correlated with preoperative logMAR BCVA in the better-seeing eye (P < .001). The postoperative VFQ-25 composite score exhibited significant correlation with postoperative logMAR BCVA in the worse-seeing eye (P < .0001) as well as the better-seeing eye (P < .0001). Similar significant correlations were also observed between the VFQ-25 composite score and letter contrast sensitivity. Conclusions Vitrectomy for PDR significantly improves VR-QOL. The current study quantitatively indicates that VR-QOL in PDR patients depends on visual acuity and contrast sensitivity in the better-seeing eye preoperatively and in both the better-seeing and worse-seeing eyes postoperatively.
URI: http://hdl.handle.net/2241/103727
Rights: © 2008 Elsevier Inc.
Text Version: author
Appears in Collections:American Journal of Ophthalmology
大鹿 哲郎 (Oshika Tetsuro)
平岡 孝浩 (Hiraoka Takahiro)
岡本 芳史 (Okamoto Yoshifumi)
岡本 史樹 (Okamoto Fumiki)

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